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What Causes Diabetes And Types Of Diabetes
A healthy diet, regular exercise, and culturally sensitive care may be helpful in preventing and controlling diabetes, say researchers. The findings are based on recent reviews that suggest that a healthy diet and exercise can help prevent diabetes, and that patients from ethnic minorities do better with diabetes education that takes their language and culture into account.
What Is Tonsilitis
Tonsillitis is an infection of the tonsils, caused by either bacteria or viruses. Tonsils are groups of tissue, similar to the lymph nodes or 'glands' that circle the throat. This circle of tissue is part of a ring of glandular tissue around the throat called Waldeyer's ring, and the tonsils are found on either side of the back of the throat.
Heart Attack Causes, Symptoms And Signs
The blood supply to the heart is usually stopped by a blood clot in the coronary arteries, causing the heart attack. The arteries are narrowed in places due to 'plaques' - a build-up of the fatty substance cholesterol over many years.
Arthritis Medical Advice And Types Of Arthritis
In order to have an understanding of the two major types of arthritis, it is essential to know a little about the function and appearance of a joint. A joint is designed to allow smooth movement of two bones, one against the other.
What Causes Asthma And Asthma Treatment
Asthma is a condition that affects your airways - the small tubes that carry air in and out of the lungs. People with asthma have airways that are almost always red and sensitive, inflamed.
Uterine Fibroids
Uterine fibroids can cause infertility by presenting as a space occupying lesion; by contiguous enlargement and subsequent blockade of the tubes, by formation of adhesions, by exhibiting heavy menstrual flow causing symptomatic anemia and causing irregularities of menstruation and hormonal imbalance, and by causing discomfort and pain during intercourse.
An assessment of patients with adult Tourette syndrome (TS) to identify clinical factors that contribute to psychosocial and occupational disabilities resulting from the vocal or motor tics that define TS found that anxiety/panic disorder may be the most disabling psychiatric condition associated with the disorder.
The results of the study, based on the Global Assessment of Functioning (GAF) scale, will be used to identify patients who are more likely to have or develop significant disabilities related either to the severity of their tics, or to the psychiatric disorders associated with TS, such as obsessive-compulsive disorder, mood disorders and drug or alcohol abuse.
Results were presented at the 14th International Congress on Parkinson’s Disease and Movement Disorders, being held in Buenos Aires, Argentina, June 14-17.
David G. Lichter, MD, professor of clinical neurology in the University at Buffalo’s School of Medicine and Biomedical Sciences, is first author.
“Our study identified the most significant predictors of disability, says Lichter. “Now having identified these at-risk patients, we can follow them more closely and begin appropriate interventions as early as possible.”
Lichter also noted that the finding of anxiety/panic disorder as the most-disabling psychiatric disorder associated with TS was unexpected.
“The main surprise was that depression was not a major predictor of psychosocial or occupational disability in these patients,” says Lichter. “Depression has been identified as an important predictor of quality of life in TS.
Tics, both motor and vocal, are the primary symptoms of Tourette syndrome. Vocal tics are involuntary sounds, such as whistles, hums, or throat clearing. Complex vocal tics can be repeating words or phrases or involuntary swearing. Motor tics are muscle spasms, such as involuntary eye blinks, shoulder shrugs, repetitive kicking, head jerks, eye darts and nose twitches.
In most patients, tics wane after mid-to-late adolescence. However, the study data indicates that in those patients whose tics persist into adulthood, tic severity remains the primary factor contributing to global psychosocial and occupational disability, according to Lichter.
“In many TS adults, motor tics remain more enduring and prominent than vocal tics and, in our study, motor tics were more severe overall than vocal tics and were more closely correlated with GAF scale score,” says Lichter.
The study involved 66 patients — 45 male and 21 female — who had been followed for an average of 8.2 years at a UB-based TS clinic. They ranged in age from 20 to 80.
Results showed that nearly 32 percent were diagnosed with obsessive-compulsive disorder (OCD), while 62 percent showed OCD behavior. Nearly 29 percent had anxiety/panic disorder with another 21 percent exhibiting anxiety symptoms.
Prevalence of other TS-associated conditions were depression (16.7 percent), depressed mood (12.1 percent), bipolar disorder (12.1 percent), rage attacks and severe self-injury behavior (4.5 percent), childhood ADHD history (33.3 percent), adult ADD (18.2 percent), substance-use disorder (22.7 percent) and psychosis and restless legs syndrome (1.5 percent).
In the future Lichter and colleagues plan to collect prospective data on both quality of life and psychosocial and occupational functioning in TS patients.
“We will look more closely at the interactions of tic severity, mood disorders, substance abuse and social support systems and determine how these issues relate to personal and social/occupational adjustment,” Lichter says.
“We hope this information will help us improve the lives of our TS patients, especially those who are at highest risk for a poor outcome.”
Sarah G. Finnegan, MD, PhD, UB assistant professor of neurology, is co-author of the study.
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